Development of a canine nociceptive thermal escape model
نویسندگان
چکیده
منابع مشابه
Intrathecal substance p-saporin attenuates operant escape from nociceptive thermal stimuli.
Destruction of neurons in the superficial dorsal horn that express substance P receptor (NK-1R) has been reported to block development of behavioral hypersensitivity following peripheral sensitization of nociceptors. Baseline sensitivity was not altered in these rat models that assessed innate reflex responses (i.e. hind-paw withdrawal to thermal or mechanical stimulation). In the present study...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2008
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2007.09.019